Parkinson's Disease Overview

FACTS

  • PD is the second most common brain disorder after Alzheimer’s disease.
  • The cells that produce dopamine, a brain chemical important to movement and mood, slowly die off.
  • The decrease in dopamine causes both motor and non-motor symptoms.
  • PD slowly progresses as more cells stop functioning.

SYMPTOMS

Motor

  • Tremor or rhythmic shaking of arms, legs, chin, or lip
  • Slow, small, and stiff movement
  • Shuffling gait
  • Impaired balance and falls
  • Soft or hoarse voice

Non-motor 

  • Neuropsychiatric
    • Depression
    • Anxiety
    • Apathy
    • Late symptoms
      • Hallucinations
      • Delusions
      • Dementia
  • Autonomic abnormalities
    • Read the website document Autonomic Abnormalities for more information.
  • Sleep disorders
    • Insomnia
    • Excessive sleep
    • Sleep apnea
    • Nightmares
    • Acting out dreams including screaming, kicking, and punching

RISK FACTORS

  • Advancing age with average onset in the 60’s
  • 5-10% of people with PD have a family history
  • Repeated head trauma
  • REM behavior disorder

DIAGNOSIS

  • A diagnosis is usually made by looking for the key motor symptoms and ruling out other conditions, such as:
  • Multiple strokes
  • Exposure to certain toxins
  • Some psychiatric medications
  • A DaTscan is a special brain scan that can help diagnose PD.

TREATMENT

  • Motor symptoms are treated with medications that mimic dopamine.
  • Non-motor symptoms are treated in various ways.
  • Exercise is essential for managing the motor symptoms and can slow the progression of PD.

More on Parkinson's Disease

Parkinson’s Disease Diary

Keeping a symptom diary helps fine-tune your treatment

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Inbrija

Detailed instructions for use

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Kynmobi

Detailed instructions for use

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Constipation

Choosing high fiber foods can help reduce constipation.

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Drug Induced Movement Disorders

Many therapeutic medicines and illicit drugs can cause movement disorders.

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Parkinson’s Disease Dementia

Also known as Lewy Body Dementia

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Impulse Control Disorders

ICD is possible while being treated with dopamine agonists.

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Orthostatic Hypotension

Changing position causes a drop in blood pressure.

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Autonomic Abnormalities in Parkinson’s Disease

The nervous system does not work properly and is unable to regulate body functions.

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Advanced Treatments For Parkinson’s Disease

Advanced treatments that address symptoms that normal medications may not.

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